Copyright 1997 By: Chris Van Deelen chrisv@nucleus.com I found the information to write up these diseases on a very interesting and Informative web site called 'Outbreak'. This site has an active outbreak listing, plus information regarding some of the deadliest disease's known to mankind. If it wasn't for this web page, I would not have been able to create this dreaded nasty to be used with the disease system I wrote up for The Morrow Project. If interested, the address for the web site is listed below: www.outbreak.org/cgi-unreg/dynaserve.exe/index.html Bubonic Plague, Septicemic plague Bubonic Plague SU - (E) - ST - 1D4+2 Days - 4 - 2 hours Medium headache, coughing boughts, pain, ulceration (occure only in groin, armpits, or cervical areas). Septicemic plague SU - (E) - CON - 1D4+2 Days - 2 Hours Medium headache, coughing boughts, pain, Rhuematoid condition in arms and legs. The varieties differ as to what part of the body the disease primarily manifests itself. Bubonic plague is centered on the lymphatic system, creating swelling lymph nodes, or buboes, from which it derives it's name. Septicemic plague indicates the disease has entered the bloodstream. Typical symptoms of plague include sudden onset of fever, shaking chills, headache, muscle pains, malaise, prostration, and often gastrointestinal symptoms. Persons with bubonic plague develop infected, swollen, lymph nodes (buboes). These buboes usually occur in the groin, armpits, or cervical areas. Complications of septicemia include septic shock, consumptive coagulopathy (a blood clotting disorder), coma, and meningitis (inflammation of membranes surrounding the brain or spinal chord). The incubation period for bubonic cases is usually 3-6 days, but occasionally can be longer. The most commonly affected sites are the lymph nodes nearest the initial site of infection. As Y. pestis multiplies in the lymph nodes, they become highly swollen, collect fluid, and become extremely tender. Such swollen lymph nodes are termed buboes, hence bubonic, and are the most readily identifiable manifestation of plague. Y. pestis also can invade the bloodstream (septicemic plague). If Y. pestis invades the bloodstream, it can spread to other sites in the body, including the liver, kidneys, spleen, lungs, and occasionally the meninges (membranes surrounding the brain or spinal chord) and eyes. Infrequently, Y. pestis causes ulcers at the point of initial infection. The most common route of infection for humans is through an insect vector (fleas). A possible scenario would be transmission via a flea which was feeding on a wild plague host, the flea could be transferred to a domestic pet, then brought home to infect the human owner. Infected animals, wild or domestic, can also infect humans directly, by scratching or biting. Person-to-person transmission in the absence of symptoms is extremely unlikely. A survivor cannot transmit Plague to others after she or he has fully recovered. Plague can be treated successfully with antibiotics if initiated early in the course of illness. Recurrence of plague in persons who survive an initial bout of the disease is rare but has been reported. Persons who recover from plague are likely to be immune to reinfection for some months to years afterwards but the duration of this immunity will vary from person to person